Auditory toxicity in late preterm and term neonates with severe jaundice.

ABSTRACT:

Aim

Jaundice may cause auditory toxicity (auditory neuropathy and hearing loss). However, total serum bilirubin (TSB) does not discriminate neonates at risk for auditory toxicity. We compared TSB, bilirubin:albumin molar ratio (BAMR), and unbound bilirubin for their association with auditory toxicity in neonates with severe jaundice (TSB ≥342μmol/L, or that met exchange transfusion).

Method

Neonates greater or equal to 34 weeks gestational age with severe jaundice during the first 2 postnatal weeks were eligible for prospective cohort study, unless they had craniofacial malformations, chromosomal disorders, toxoplasmosis, other infections, rubella, cytomegalovirus, herpes simplex infections, surgery, or family history of congenital deafness.

Results

Twenty-eight out o

SUBMITTER: Amin SB 

PROVIDER: S-EPMC5288130 | biostudies-literature | 2017 Mar

REPOSITORIES: biostudies-literature