Ontology highlight
ABSTRACT:
SUBMITTER: Shinozaki A
PROVIDER: S-EPMC5289493 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Shinozaki Ayako A Misawa Kenichiro K Ikeda Yuko Y Haraguchi Atsushi A Kamagata Mayo M Tahara Yu Y Shibata Shigenobu S
PloS one 20170202 2
Flavonoids are natural polyphenols that are widely found in plants. The effects of flavonoids on obesity and numerous diseases such as cancer, diabetes, and Alzheimer's have been well studied. However, little is known about the relationships between flavonoids and the circadian clock. In this study, we show that continuous or transient application of flavonoids to the culture medium of embryonic fibroblasts from PER2::LUCIFERASE (PER2::LUC) mice induced various modifications in the circadian clo ...[more]