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Bacteriophage MAV1 is not associated with virulence of Mycoplasma arthritidis.

ABSTRACT: Previous studies demonstrated that Mycoplasma arthritidis strain 158 acquired a high degree of virulence upon lysogenization with bacteriophage MAV1. In the present study, the association between MAV1 and virulence was reexamined by creating new lysogens of 158 and of a relatively avirulent mutant, strain 158-1. In the absence of lysogenization, 158 was more virulent than expected. The virulence of 158 and 158-1 did not increase upon lysogenization. A major antigenic difference between 158 and 158-1 was identified that is unrelated to MAV1 and could account for the difference in virulence.

SUBMITTER: Clapper B

PROVIDER: S-EPMC529157 | biostudies-literature | 2004 Dec

REPOSITORIES: biostudies-literature

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Bacteriophage MAV1 is not associated with virulence of Mycoplasma arthritidis.

Clapper Brenda B Tu Anh-Hue T AH Simmons Warren L WL Dybvig Kevin K

Infection and immunity 20041201 12

Previous studies demonstrated that Mycoplasma arthritidis strain 158 acquired a high degree of virulence upon lysogenization with bacteriophage MAV1. In the present study, the association between MAV1 and virulence was reexamined by creating new lysogens of 158 and of a relatively avirulent mutant, strain 158-1. In the absence of lysogenization, 158 was more virulent than expected. The virulence of 158 and 158-1 did not increase upon lysogenization. A major antigenic difference between 158 and 1 ...[more]

PMID: 15557660

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