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VanE-type vancomycin-resistant Enterococcus faecalis clinical isolates from Australia.


ABSTRACT: Three distinct Enterococcus faecalis VanE-type isolates-BM4574, BM4575, and BM4576-obtained in Australia were studied. Expression of the resistance genes was constitutive in BM4575, probably due to a 2-bp deletion into the vanSE gene, and inducible in BM4574 and BM4576. Transcription analysis of the vanE operons suggested that the five genes were cotranscribed from an initiation site located 25 bp upstream from the ATG start codon of vanE.

SUBMITTER: Abadia-Patino L 

PROVIDER: S-EPMC529234 | biostudies-literature | 2004 Dec

REPOSITORIES: biostudies-literature

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VanE-type vancomycin-resistant Enterococcus faecalis clinical isolates from Australia.

Abadía-Patiño Lorena L   Christiansen Keryn K   Bell Jan J   Courvalin Patrice P   Périchon Bruno B  

Antimicrobial agents and chemotherapy 20041201 12


Three distinct Enterococcus faecalis VanE-type isolates-BM4574, BM4575, and BM4576-obtained in Australia were studied. Expression of the resistance genes was constitutive in BM4575, probably due to a 2-bp deletion into the vanSE gene, and inducible in BM4574 and BM4576. Transcription analysis of the vanE operons suggested that the five genes were cotranscribed from an initiation site located 25 bp upstream from the ATG start codon of vanE. ...[more]

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