Ontology highlight
ABSTRACT:
SUBMITTER: Kim BG
PROVIDER: S-EPMC5292703 | biostudies-literature | 2017 Feb
REPOSITORIES: biostudies-literature
Kim Bo Gyung BG Kim Jin Young JY Jung JinSei J Moon In Seok IS Yoon Joo-Heon JH Choi Jae Young JY Kim Sung Huhn SH
Scientific reports 20170206
The endolymphatic sac (ES) is a cystic structure of the inner ear connected to the cochlea and vestibule, which plays a role in regulating ion homeostasis in inner ear fluid. Disruption of ion homeostasis can cause inner ear disorders with hearing loss and dizziness, such as Meniere's disease. Herein, we found, for the first time, functional evidence for the involvement of β<sub>1</sub>- and β<sub>2</sub>-adrenergic receptors in apical electrogenic ion transport by human ES epithelium by using e ...[more]