Ontology highlight
ABSTRACT:
SUBMITTER: Chiu Y
PROVIDER: S-EPMC5294212 | biostudies-literature | 2017 Feb
REPOSITORIES: biostudies-literature
Molecular & cellular proteomics : MCP 20161209 2
We present a statistical model to estimate the accuracy of derivatized heparin and heparan sulfate (HS) glycosaminoglycan (GAG) assignments to tandem mass (MS/MS) spectra made by the first published database search application, GAG-ID. Employing a multivariate expectation-maximization algorithm, this statistical model distinguishes correct from ambiguous and incorrect database search results when computing the probability that heparin/HS GAG assignments to spectra are correct based upon database ...[more]