Ontology highlight
ABSTRACT:
SUBMITTER: Yu Z
PROVIDER: S-EPMC5294743 | biostudies-literature | 2017 Apr
REPOSITORIES: biostudies-literature
Yu Zhanru Z Huang Honglei H Reim Alexander A Charles Philip D PD Northage Alan A Jackson Dianne D Parry Ian I Kessler Benedikt M BM
Talanta 20170107
Two-dimensional gas chromatography mass spectrometry (GCxGC-MS) is utilized to an increasing extent in biomedical metabolomics. Here, we established and adapted metabolite extraction and derivatization protocols for cell/tissue biopsy, serum and urine samples according to their individual properties. GCxGC-MS analysis revealed detection of ~600 molecular features from which 165 were characterized representing different classes such as amino acids, fatty acids, lipids, carbohydrates, nucleotides ...[more]