Targeting Neural Circuits.
Ontology highlight
ABSTRACT:
SUBMITTER: Rajasethupathy P
PROVIDER: S-EPMC5296409 | biostudies-literature | 2016 Apr
REPOSITORIES: biostudies-literature
Publications
Targeting Neural Circuits.
Rajasethupathy Priyamvada P Ferenczi Emily E Deisseroth Karl K
Cell 20160401 3
Optogenetic methodology enables direct targeting of specific neural circuit elements for inhibition or excitation while spanning timescales from the acute (milliseconds) to the chronic (many days or more). Although the impact of this temporal versatility and cellular specificity has been greater for basic science than clinical research, it is natural to ask whether the dynamic patterns of neural circuit activity discovered to be causal in adaptive or maladaptive behaviors could become targets fo ...[more]
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