Ontology highlight
ABSTRACT:
SUBMITTER: Kwon H
PROVIDER: S-EPMC5297917 | biostudies-literature | 2017 Feb
REPOSITORIES: biostudies-literature
Kwon Hanna H Smith Oliver O Raven Emma Lloyd EL Moody Peter C E PC
Acta crystallographica. Section D, Structural biology 20170201 Pt 2
X-ray protein crystallography has, through the determination of the three-dimensional structures of enzymes and their complexes, been essential to the understanding of biological chemistry. However, as X-rays are scattered by electrons, the technique has difficulty locating the presence and position of H atoms (and cannot locate H<sup>+</sup> ions), knowledge of which is often crucially important for the understanding of enzyme mechanism. Furthermore, X-ray irradiation, through photoelectronic e ...[more]