Ontology highlight
ABSTRACT:
SUBMITTER: Narayanan S
PROVIDER: S-EPMC5298449 | biostudies-literature | 2017 Jan
REPOSITORIES: biostudies-literature
Therapeutic advances in medical oncology 20160916 1
Patients with relapsed or refractory urothelial carcinoma (UC) have poor prognosis coupled with few options for systemic treatment. The role of angiogenesis in the evolution of cancers has been established, and studies have shown that it plays a key role in the pathogenesis of UC. Many targeted agents have been used in phase I-II trials for the treatment of UC, with encouraging but modest results. Recently, studies combining angiogenesis inhibitors with other chemotherapeutic agents were able to ...[more]