Ontology highlight
ABSTRACT:
SUBMITTER: Rignault-Clerc S
PROVIDER: S-EPMC5299447 | biostudies-literature | 2017 Feb
REPOSITORIES: biostudies-literature
Rignault-Clerc Stéphanie S Bielmann Christelle C Liaudet Lucas L Waeber Bernard B Feihl François F Rosenblatt-Velin Nathalie N
Scientific reports 20170209
Brain Natriuretic Peptide (BNP) injections in adult "healthy" or infarcted mice led to increased number of non-myocyte cells (NMCs) expressing the nuclear transcription factor Nkx2.5. The aim of this study was to identify the nature of the cells able to respond to BNP as well as the signaling pathway involved. BNP treatment of neonatal mouse NMCs stimulated Sca-1<sup>+</sup> cell proliferation. The Sca-1<sup>+</sup> cells were characterized as being a mixed cell population involving fibroblasts ...[more]