Post-challenge insulin concentration is useful for differentiating between coronary artery disease and cardiac syndrome X in subjects without known diabetes mellitus.

ABSTRACT:

Background

Cardiac syndrome X (CSX) is characterized by angina pectoris but with patent coronary arteries. Our previous study demonstrated that subjects with CSX had a higher fasting insulin-resistance (IR) than the controls. However, few studies have investigated the degree of IR, including oral glucose tolerance test (OGTT)-derived indices and profiles of metabolic abnormalities between CSX and coronary artery disease (CAD).

Methods

Ninety-two CSX and 145 CAD subjects without known diabetes mellitus (DM) underwent coronary angiogram (CAG) for angina pectoris and also agreed to receive OGTT and glycated hemoglobin (HbA_1C) evaluations for screening abnormal glucose regulation and IR.

Results

CAD group had more subjects with metabolically unhealthy obesity (

SUBMITTER: Liang KW 

PROVIDER: S-EPMC5299675 | biostudies-literature | 2017

REPOSITORIES: biostudies-literature