An investigation of cerebrovascular lesions in dementia with Lewy bodies compared to Alzheimer's disease.
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ABSTRACT:
SUBMITTER: Sarro L
PROVIDER: S-EPMC5303194 | biostudies-literature | 2017 Mar
REPOSITORIES: biostudies-literature
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An investigation of cerebrovascular lesions in dementia with Lewy bodies compared to Alzheimer's disease.
Sarro Lidia L Tosakulwong Nirubol N Schwarz Christopher G CG Graff-Radford Jonathan J Przybelski Scott A SA Lesnick Timothy G TG Zuk Samantha M SM Reid Robert I RI Raman Mekala R MR Boeve Bradley F BF Ferman Tanis J TJ Knopman David S DS Comi Giancarlo G Filippi Massimo M Murray Melissa E ME Parisi Joseph E JE Dickson Dennis W DW Petersen Ronald C RC Jack Clifford R CR Kantarci Kejal K
Alzheimer's & dementia : the journal of the Alzheimer's Association 20160810 3
<h4>Introduction</h4>Cerebrovascular lesions on MRI are common in Alzheimer's disease (AD) dementia, but less is known about their frequency and impact on dementia with Lewy bodies (DLB).<h4>Methods</h4>White-matter hyperintensities (WMHs) and infarcts on MRI were assessed in consecutive DLB (n = 81) and AD dementia (n = 240) patients and compared to age-matched and sex-matched cognitively normal subjects (CN) from a population-based cohort.<h4>Results</h4>DLB had higher WMH volume compared to C ...[more]
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