Ontology highlight
ABSTRACT:
SUBMITTER: Paillamanque J
PROVIDER: S-EPMC5305069 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Paillamanque Joaquin J Sanchez-Tusie Ana A Carmona Emerson M EM Treviño Claudia L CL Sandoval Carolina C Nualart Francisco F Osses Nelson N Reyes Juan G JG
PloS one 20170213 2
Arachidonic acid (AA), a compound secreted by Sertoli cells (SC) in a FSH-dependent manner, is able to induce the release of Ca2+ from internal stores in round spermatids and pachytene spermatocytes. In this study, the possible site(s) of action of AA in round spermatids, the signalling pathways associated and the intracellular Ca2+ stores targeted by AA-induced signalling were pharmacologically characterized by measuring intracellular Ca2+ using fluorescent Ca2+ probes. Our results suggest that ...[more]