Edible solid lipid nanoparticles (SLN) as carrier system for antioxidants of different lipophilicity.
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ABSTRACT:
SUBMITTER: Oehlke K
PROVIDER: S-EPMC5305235 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
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Edible solid lipid nanoparticles (SLN) as carrier system for antioxidants of different lipophilicity.
Oehlke Kathleen K Behsnilian Diana D Mayer-Miebach Esther E Weidler Peter G PG Greiner Ralf R
PloS one 20170213 2
Ferulic acid (FA) and tocopherol (Toc) loaded solid lipid nanoparticles (SLN) were prepared by a hot homogenisation method. The particle size distribution, zeta potential and melting behaviour of the SLN as well as the stability, encapsulation efficiency and radical scavenging activity of FA and Toc in the SLN were analysed. The different formulations containing up to 2.8 mg g-1 of FA or Toc were stable during at least 15 weeks of storage at room temperature. Despite partial degradation and / or ...[more]
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