Circulating microRNAs Correlated with Bone Loss Induced by 45 Days of Bed Rest.
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ABSTRACT:
SUBMITTER: Ling S
PROVIDER: S-EPMC5306370 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Publications
Circulating microRNAs Correlated with Bone Loss Induced by 45 Days of Bed Rest.
Ling Shukuan S Zhong Guohui G Sun Weijia W Liang Fengji F Wu Feng F Li Hongxing H Li Yuheng Y Zhao Dingsheng D Song Jinping J Jin Xiaoyan X Wu Xiaorui X Song Hailin H Li Qi Q Li Yinghui Y Chen Shanguang S Xiong Jianghui J Li Yingxian Y
Frontiers in physiology 20170214
The purpose of this study was to find the circulating microRNAs (miRNAs) co-related with bone loss induced by bed rest, and testify whether the selected miRNAs could reflect the bone mineral status of human after bed-rest. We analyzed plasma miRNA levels of 16 subjects after 45 days of -6° head-down tilt bed rest, which is a reliable model for the simulation of microgravity. We characterize the circulating miRNA profile in individuals after bed rest and identify circulating miRNAs which can best ...[more]
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