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WHO water quality standards Vs Synergic effect(s) of fluoride, heavy metals and hardness in drinking water on kidney tissues.

ABSTRACT: Despite WHO standards, waterborne diseases among the human being are rising alarmingly. It is known that the prolong exposure to contaminated water has major impact on public health. The effect of chemical contaminations in drinking water on human being is found to be chronic rather than acute and hence can be defined "consumption of contaminated drinking water could be a silent killer". As the WHO recommended water quality standards are only for individual element and synergic effects of trace metals and anions have not been considered, investigation of synergic effects of trace metals and anions and their effect on human being is of prime important research. By an animal trial, we investigated the synergic effect(s) of heavy metals, aluminium, arsenic, fluoride and hardness in drinking water on kidney tissues of mice. Our investigation strongly suggests existing of a synergic effect especially among Cd, F and hardness of water which could lead to severe kidney damage in mice, even at WHO maximum recommended levels. Hence, the synergic effect(s) of trace metals, fluoride and hardness present in drinking water should be investigated meticulously when stipulating the water quality at WHO maximum recommended levels.

SUBMITTER: Wasana HM

PROVIDER: S-EPMC5307334 | biostudies-literature | 2017 Feb

REPOSITORIES: biostudies-literature

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WHO water quality standards Vs Synergic effect(s) of fluoride, heavy metals and hardness in drinking water on kidney tissues.

Wasana Hewa M S HM Perera Gamage D R K GD Gunawardena Panduka De S PS Fernando Palika S PS Bandara Jayasundera J

Scientific reports 20170214

Despite WHO standards, waterborne diseases among the human being are rising alarmingly. It is known that the prolong exposure to contaminated water has major impact on public health. The effect of chemical contaminations in drinking water on human being is found to be chronic rather than acute and hence can be defined "consumption of contaminated drinking water could be a silent killer". As the WHO recommended water quality standards are only for individual element and synergic effects of trace ...[more]

PMID: 28195172

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Project description:BackgroundBesides their benefits, heavy metals are toxic, persistent, and hazardous to human health, even at their lower concentrations. Consumption of unsafe concentrations of food contaminated with heavy metals may lead to the disruption of numerous biological and biochemical processes in the human body. In developing country including Ethiopia, where untreated or partially treated wastewater is used for agricultural purposes, the problems related to the consumption foods contaminated with heavy metals may poses highest risk to human health. Therefore, this review was aimed to determine the public health implications of heavy metals in foods and drinking water in Ethiopia.MethodsThe articles published from 2016 to 2020 were identified through systematic searches of electronic databases that include MEDLINE/PubMed, EMBASE, CINAH, Google Scholar, WHO, and FAO Libraries. The data was extracted using a predetermined data extraction form using Microsoft Excel, 2016. The methodological quality of the included studies was assessed using mixed methods appraisal tool (MMAT) version 2018 and Joanna Briggs Institute Critical Appraisal tools to determine the relevance of the studies. Finally, the results were evaluated based on the FAO/WHO guidelines for foods and drinking water.ResultsA total of 1019 articles published from 2016 to 2020 were searched from various electronic databases and by manual searching on Google. Following the initial screening, 317 articles were retrieved for evaluation and 49 articles were assessed for eligibility, of which 21 studies were included in the systematic review. The mean concentration of Cr, Cd, Pb, As, Hg, Zn, Cu, Ni, Co, Fe and Mn in fruits and vegetables ranged from 2.068-4.29, 0.86-1.37, 1.90-4.70, 1.01-3.56, 3.43-4.23, 19.18-98.15, 4.39-9.42, 1.037-5.27, 0.19-1.0, 199.5-370.4, 0.26-869 mg/kg, respectively. The mean concentration Cr, Cd, Pb, As, Zn, and Fe in meat and milk ranged from 1.032-2.72, 0.233-0.72, 1.32-3.15, 0.79-2.96, 78.37-467.7, and 505.61-3549.9 mg/kg, respectively. The mean concentration of Cr, Cd, Pb, Zn, and Cu in drinking water ranged 0.0089-0.054, 0.02-0.0237, 0.005-0.369, 0.625-2.137, and 0.176-1.176 ml/L, respectively. The mean concentration of Cr, Cd, Pb, Zn, Cu, Ni, Co, Fe, and Mn in other edible cereals ranged from 0.973-2.165, 0.424-0.55, 0.65-1.70, 70.51-81.58, 14.123-15.98, 1.89-13.8, 1.06-1.59, 67.866-110.3, and 13.686-15.4 mg/kg, respectively.ConclusionThis systematic review identified heavy metals in foods and drinking water and determined their public health implications. The results of this finding imply that the majority of the studies reported high concentrations of toxic heavy metals in foods and drinking water that are hazardous to human health. Therefore, effective food safety and risk-based food quality assessment are essential to protect the public health.

Project description:The disposal of polymer post-treatment sludge (PTS) from Barekese Water Treatment Plants (WTPs) as organic fertilizer and aquatic feed is a common practice in Ghana, necessitating a thorough evaluation of its ecological and human health risks. This study aims to assess the suitability of PTS samples for soil amendment and fish feed, scrutinizing potential hazards to consumer health and soil. PTS samples were collected from five distinct lateral sections of three clariflocculator tanks. Potentially toxic metals such as Cd, Zn, Pb, Cu, Ni, and Cr were determined using a flame atomic absorption spectrophotometer. The mean concentration of 7.82 ± 2.43, 0.31 ± 0.021, and 0.78 ± 0.042 mg/kg for Mn, Zn, and Pb respectively. The concentrations of Ni, Cr, and Cd were below their detection limits (BDL) in all PTS samples. Upon detailed exposure assessment, ingestion emerged as the primary exposure route for both adults and children, with non-cancer risks (NCR) determined to be below 1 for both age groups. Additionally, an exploration of potential cancer risks (CR) associated with heavy metal exposure in the PTS samples revealed values below the tolerable intake levels ranging from 10-4 to 10-6 for both adults and children (10-8 and 10-9, respectively). This study also employs various ecological indices, such as Nemerow's synthetic pollution index (PN), single factor pollution index (PI), geo-accumulation index (Igeo), contamination factor (CF), potential ecological risk index (PERI), pollution load index (PLI), polymetallic contaminant index (IPD), and ecological risk index (ERI). These indices consistently highlight a low contamination status and ecological sensitivity. Consequently, the study indicates that the presence of metals in the PTS samples does not pose a significant threat to the surrounding environment and human health. Furthermore, this research underscores the inadequacy of relying solely on regulatory limit values in assessing the health risks of waste materials. Such comprehensive assessments are crucial for safeguarding aquatic and human populations.

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WHO water quality standards Vs Synergic effect(s) of fluoride, heavy metals and hardness in drinking water on kidney tissues.

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WHO water quality standards Vs Synergic effect(s) of fluoride, heavy metals and hardness in drinking water on kidney tissues.

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