CD73 is associated with poor prognosis in HNSCC.
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ABSTRACT:
SUBMITTER: Ren ZH
PROVIDER: S-EPMC5308683 | biostudies-literature | 2016 Sep
REPOSITORIES: biostudies-literature
Publications
CD73 is associated with poor prognosis in HNSCC.
Ren Zhen-Hu ZH Lin Cheng-Zhong CZ Cao Wei W Yang Rong R Lu Wei W Liu Zhe-Qi ZQ Chen Yi-Ming YM Yang Xi X Tian Zhen Z Wang Li-Zhen LZ Li Jiang J Wang Xu X Chen Wan-Tao WT Ji Tong T Zhang Chen-Ping CP
Oncotarget 20160901 38
CD73 is a cell surface immunosuppressive enzyme involved in tumor progression and metastasis. While patients whose cancer cells express elevated CD73 are typically associated with an unfavorable outcome, the clinical impact of CD73 expression in patients with Head and neck squamous cell carcinoma (HNSCC) remains unclear. In the present study, we investigated the prognostic significance of CD73 in HNSCC using gene and protein expression analyses. Our results demonstrate that high levels of CD73 a ...[more]
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