Ontology highlight
ABSTRACT:
SUBMITTER: Zhai H
PROVIDER: S-EPMC5308830 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Zhai Huihong H Zhai Huihong H Shi Yongquan Y Chen Xiong X Wang Jun J Lu Yuanyuan Y Zhang Faming F Liu Zhengxiong Z Lei Ting T Fan Daiming D
PloS one 20170214 2
CacyBP/SIP is a component of the ubiquitin pathway and is overexpressed in several transformed tumor tissues, including colon cancer, which is one of the most common cancers worldwide. It is unknown whether CacyBP/SIP promotes the proliferation of colon cancer cells. This study examined the expression level, subcellular localization, and binding activity of CacyBP/SIP in human colon cancer cells in the presence and absence of the hormone gastrin. We found that CacyBP/SIP was expressed in a high ...[more]