Ontology highlight
ABSTRACT:
SUBMITTER: Han E
PROVIDER: S-EPMC5309710 | biostudies-literature | 2017 Feb
REPOSITORIES: biostudies-literature
Han Eunjung E Carbonetto Peter P Curtis Ross E RE Wang Yong Y Granka Julie M JM Byrnes Jake J Noto Keith K Kermany Amir R AR Myres Natalie M NM Barber Mathew J MJ Rand Kristin A KA Song Shiya S Roman Theodore T Battat Erin E Elyashiv Eyal E Guturu Harendra H Hong Eurie L EL Chahine Kenneth G KG Ball Catherine A CA
Nature communications 20170207
Despite strides in characterizing human history from genetic polymorphism data, progress in identifying genetic signatures of recent demography has been limited. Here we identify very recent fine-scale population structure in North America from a network of over 500 million genetic (identity-by-descent, IBD) connections among 770,000 genotyped individuals of US origin. We detect densely connected clusters within the network and annotate these clusters using a database of over 20 million genealog ...[more]