Ontology highlight
ABSTRACT:
SUBMITTER: Currie MA
PROVIDER: S-EPMC5311493 | biostudies-literature | 2017 Mar
REPOSITORIES: biostudies-literature
RNA (New York, N.Y.) 20161208 3
<i>S</i>-adenosylmethionine (SAM)-dependent methyltransferases regulate a wide range of biological processes through the modification of proteins, nucleic acids, polysaccharides, as well as various metabolites. TYW3/Taw3 is a SAM-dependent methyltransferase responsible for the formation of a tRNA modification known as wybutosine and its derivatives that are required for accurate decoding in protein synthesis. Here, we report the crystal structure of Taw3, a homolog of TYW3 from <i>Sulfolobus sol ...[more]