Ontology highlight
ABSTRACT:
SUBMITTER: Anderson AJ
PROVIDER: S-EPMC5312249 | biostudies-literature | 2017 Feb
REPOSITORIES: biostudies-literature
Stem cell reports 20170201 2
We previously showed the efficacy of multiple research cell lines (RCLs) of human CNS neural stem cells (HuCNS-SCs) in mouse and rat models of thoracic spinal cord injury (SCI), supporting a thoracic SCI clinical trial. Experts recommend in vivo preclinical testing of the intended clinical cell lot/line (CCL) in models with validity for the planned clinical target. We therefore tested the efficacy of two HuCNS-SC lines in cervical SCI: one RCL, and one CCL intended for use in the Pathway Study o ...[more]