Ontology highlight
ABSTRACT:
SUBMITTER: Shekar S
PROVIDER: S-EPMC5312517 | biostudies-literature | 2016 Jul
REPOSITORIES: biostudies-literature
Shekar Siddharth S Niedzwiecki David J DJ Chien Chen-Chi CC Ong Peijie P Fleischer Daniel A DA Lin Jianxun J Rosenstein Jacob K JK Drndić Marija M Shepard Kenneth L KL
Nano letters 20160627 7
Despite the potential for nanopores to be a platform for high-bandwidth study of single-molecule systems, ionic current measurements through nanopores have been limited in their temporal resolution by noise arising from poorly optimized measurement electronics and large parasitic capacitances in the nanopore membranes. Here, we present a complementary metal-oxide-semiconductor (CMOS) nanopore (CNP) amplifier capable of low noise recordings at an unprecedented 10 MHz bandwidth. When integrated wi ...[more]