Ontology highlight
ABSTRACT:
SUBMITTER: Jiang MX
PROVIDER: S-EPMC5314404 | biostudies-literature | 2017 Feb
REPOSITORIES: biostudies-literature
Jiang Mei-Xiu MX Hong Xuan X Liao Bin-Bin BB Shi Shui-Zhen SZ Lai Xiao-Fang XF Zheng Huai-Yu HY Xie Lin L Wang Yuan Y Wang Xiao-Lei XL Xin Hong-Bo HB Fu Mingui M Deng Ke-Yu KY
Scientific reports 20170217
Activated macrophages play an important role in many inflammatory diseases including septic shock and atherosclerosis. However, the molecular mechanisms limiting macrophage activation are not completely understood. Members of the tripartite motif (TRIM) family have recently emerged as important players in innate immunity and antivirus. Here, we systematically analyzed mRNA expressions of representative TRIM molecules in human THP1-derived macrophages activated by different toll-like receptor (TL ...[more]