Ontology highlight
ABSTRACT:
SUBMITTER: Ahn SB
PROVIDER: S-EPMC5314440 | biostudies-literature | 2017 Apr
REPOSITORIES: biostudies-literature
Ahn Su-Bi SB Lee Sang Bong SB Singh Thoudam Debraj TD Cho Sung Jin SJ Kim Sang Kyoon SK Lee In-Kyu IK Jeong Shin Young SY Ahn Byeong-Cheol BC Lee Jaetae J Lee Sang-Woo SW Jeon Yong Hyun YH
Translational oncology 20170216 2
Here, we sought to monitor bone marrow-derived dendritic cell (BMDC) migration and antitumor effects using a multimodal reporter imaging strategy in living mice. BMDCs were transduced with retroviral vector harboring human sodium iodide symporter (hNIS, nuclear imaging reporter), firefly luc2 (optical imaging reporter), and thy1.1 (surrogate marker of NIS and luc2) genes (BMDC/NF cells). No significant differences in biological functions, including cell proliferation, antigen uptake, phenotype e ...[more]