Unknown

Dataset Information

0

Association of Obstructive Sleep Apnea with Episodic Memory and Cerebral Microvascular Pathology: A Preliminary Study.

ABSTRACT: To evaluate the impact of obstructive sleep apnea (OSA) on neurocognitive function and brain morphology in older adults with depression and cognitive impairment.We prospectively screened OSA with the STOP-Bang questionnaire in the last 25 patients enrolled into the Donepezil Treatment of Cognitive Impairment and Depression (DOTCODE) trial. High and low probability of OSA were defined as a STOP-Bang score of ?5 (h-OSA) and of <5 (l-OSA), respectively. Baseline magnetic resonance imaging (MRI) was used to evaluate brain morphology. The initial 16 weeks of antidepressant treatment were part of the DOTCODE trial.After 16 weeks of antidepressant treatment, the h-OSA group performed significantly worse on the Selective Reminding Test delayed recall task than the l-OSA group, controlling for baseline performance (F?=?19.1, df?=?1,22, p?

SUBMITTER: Kerner NA 

PROVIDER: S-EPMC5316492 | biostudies-literature | 2017 Mar

REPOSITORIES: biostudies-literature

Json Xml
altmetric image

Publications

Association of Obstructive Sleep Apnea with Episodic Memory and Cerebral Microvascular Pathology: A Preliminary Study.

Kerner Nancy A NA   Roose Steven P SP   Pelton Gregory H GH   Ciarleglio Adam A   Scodes Jennifer J   Lentz Cody C   Sneed Joel R JR   Devanand D P DP  

The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 20161117 3

<h4>Objectives</h4>To evaluate the impact of obstructive sleep apnea (OSA) on neurocognitive function and brain morphology in older adults with depression and cognitive impairment.<h4>Methods</h4>We prospectively screened OSA with the STOP-Bang questionnaire in the last 25 patients enrolled into the Donepezil Treatment of Cognitive Impairment and Depression (DOTCODE) trial. High and low probability of OSA were defined as a STOP-Bang score of ≥5 (h-OSA) and of <5 (l-OSA), respectively. Baseline m  ...[more]

Similar Datasets

Transcriptomics Visceral fat trancriptome in obstructive sleep apnea
2012-09-01 | E-GEOD-38792 | biostudies-arrayexpress
Transcriptomics Visceral fat trancriptome in obstructive sleep apnea
2012-09-01 | GSE38792 | GEO
Unknown Memory and obstructive sleep apnea: a meta-analysis.
| S-EPMC3543053 | biostudies-literature
Unknown Association Between Eyelid Laxity and Obstructive Sleep Apnea.
| S-EPMC5710483 | biostudies-other
Unknown Armodafinil improves wakefulness and long-term episodic memory in nCPAP-adherent patients with excessive sleepiness associated with obstructive sleep apnea.
| S-EPMC2194800 | biostudies-other
Unknown Obstructive Sleep Apnea Syndrome: A Preliminary Navigated Transcranial Magnetic Stimulation Study.
| S-EPMC7418161 | biostudies-literature
Unknown Association between Obstructive Sleep Apnea and Community-Acquired Pneumonia.
| S-EPMC4822965 | biostudies-literature
Unknown Predictors of changes in cerebral perfusion and oxygenation during obstructive sleep apnea.
| S-EPMC8648752 | biostudies-literature
Unknown Association between asthma and risk of developing obstructive sleep apnea.
| S-EPMC4334115 | biostudies-literature
Unknown Association of Obstructive Sleep Apnea with Asthma: A Meta-Analysis.
| S-EPMC5481327 | biostudies-literature