Systematic Characterization and Analysis of the Taxonomic Drivers of Functional Shifts in the Human Microbiome.
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ABSTRACT:
SUBMITTER: Manor O
PROVIDER: S-EPMC5316541 | biostudies-literature | 2017 Feb
REPOSITORIES: biostudies-literature
Publications
Systematic Characterization and Analysis of the Taxonomic Drivers of Functional Shifts in the Human Microbiome.
Manor Ohad O Borenstein Elhanan E
Cell host & microbe 20170119 2
Comparative analyses of the human microbiome have identified both taxonomic and functional shifts that are associated with numerous diseases. To date, however, microbiome taxonomy and function have mostly been studied independently and the taxonomic drivers of functional imbalances have not been systematically identified. Here, we present FishTaco, an analytical and computational framework that integrates taxonomic and functional comparative analyses to accurately quantify taxon-level contributi ...[more]
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