Ontology highlight
ABSTRACT:
SUBMITTER: Duan G
PROVIDER: S-EPMC5317030 | biostudies-literature | 2017 Feb
REPOSITORIES: biostudies-literature
Duan Guangxin G Zhang Yuanzhao Y Luan Binquan B Weber Jeffrey K JK Zhou Royce W RW Yang Zaixing Z Zhao Lin L Xu Jiaying J Luo Judong J Zhou Ruhong R
Scientific reports 20170220
Examining interactions between nanomaterials and cell membranes can expose underlying mechanisms of nanomaterial cytotoxicity and guide the design of safer nanomedical technologies. Recently, graphene has been shown to exhibit potential toxicity to cells; however, the molecular processes driving its lethal properties have yet to be fully characterized. We here demonstrate that graphene nanosheets (both pristine and oxidized) can produce holes (pores) in the membranes of A549 and Raw264.7 cells, ...[more]