Ontology highlight
ABSTRACT:
SUBMITTER: Halfvarson J
PROVIDER: S-EPMC5319707 | biostudies-literature | 2017 Feb
REPOSITORIES: biostudies-literature
Halfvarson Jonas J Brislawn Colin J CJ Lamendella Regina R Vázquez-Baeza Yoshiki Y Walters William A WA Bramer Lisa M LM D'Amato Mauro M Bonfiglio Ferdinando F McDonald Daniel D Gonzalez Antonio A McClure Erin E EE Dunklebarger Mitchell F MF Knight Rob R Jansson Janet K JK
Nature microbiology 20170213
Inflammatory bowel disease (IBD) is characterized by flares of inflammation with a periodic need for increased medication and sometimes even surgery. The aetiology of IBD is partly attributed to a deregulated immune response to gut microbiome dysbiosis. Cross-sectional studies have revealed microbial signatures for different IBD subtypes, including ulcerative colitis, colonic Crohn's disease and ileal Crohn's disease. Although IBD is dynamic, microbiome studies have primarily focused on single t ...[more]