Ontology highlight
ABSTRACT:
SUBMITTER: Wang Y
PROVIDER: S-EPMC5320652 | biostudies-literature | 2017 Feb
REPOSITORIES: biostudies-literature
Wang Yan Y Chen Lianghui L Li Fang F Bao Meihua M Zeng Jie J Xiang Ju J Luo Huaiqing H Li Jianming J Tang Liang L
Pediatric rheumatology online journal 20170221 1
<h4>Background</h4>The aim of the study was to determine whether polymorphisms in toll-like receptor 4 (TLR4) confer susceptibility to rheumatoid arthritis (RA) and juvenile idiopathic arthritis (JIA) in a central south Chinese Han population.<h4>Methods</h4>Genotyping for six well studied polymorphisms (rs4986790, rs4986791, rs10759932, rs41426344, rs11536889 and rs7873784) in TLR4 gene were conducted in 1074 unrelated patients with RA and 1692 healthy control subjects, as well as in 217 unrela ...[more]