Counts of bovine monocyte subsets prior to calving are predictive for postpartum occurrence of mastitis and metritis.

ABSTRACT: The heightened susceptibility to infectious diseases in postpartum dairy cows is often attributed to immune dysfunction associated with the transition period. However, the cell populations involved in this immune dysfunction and the dynamics between those populations are not well defined. Monocytes play a crucial role in governing initial immune response in bacterial infections. Bovine monocytes are subdivided in classical (CD14⁺/CD16^-), intermediate (CD14⁺/CD16⁺) and non-classical monocytes (CD14^-/CD16⁺) with distinct phenotypic and functional differences. This study investigated the relationship of monocyte subsets counts in blood at 42 and 14 days prior to expected calving date to occurrence of metritis and mastitis withi

SUBMITTER: Pomeroy B 

PROVIDER: S-EPMC5320682 | biostudies-literature | 2017 Feb

REPOSITORIES: biostudies-literature