Ontology highlight
ABSTRACT:
SUBMITTER: Ali NM
PROVIDER: S-EPMC5320730 | biostudies-literature | 2017
REPOSITORIES: biostudies-literature
Ali Norlaily Mohd NM Yeap Swee Keong SK Abu Nadiah N Lim Kian Lam KL Ky Huynh H Pauzi Ahmad Zaim Mat AZM Ho Wan Yong WY Tan Sheau Wei SW Alan-Ong Han Kiat HK Zareen Seema S Alitheen Noorjahan Banu NB Akhtar M Nadeem MN
Cancer cell international 20170221
<h4>Aims</h4>Curcumin is a lead compound of the rhizomes of <i>Curcuma longa</i> and possess a broad range of pharmacological activities. Chemically, curcumin is 1,3-dicarbonyl class of compound, which exhibits keto-enol tautomerism. Despite of its strong biological properties, curcumin has yet been recommended as a therapeutic agent because of its poor bioavailability.<h4>Main methods</h4>A curcumin derivative (<i>Z</i>)-3-hydroxy-1-(2-hydroxyphenyl)-3-phenylprop-2-en-1-one (DK1) was synthesize ...[more]