Ontology highlight
ABSTRACT:
SUBMITTER: Nawroth JF
PROVIDER: S-EPMC5320936 | biostudies-literature | 2016 Mar
REPOSITORIES: biostudies-literature
Nawroth Jonas F JF McDaniel Jonathan R JR Chilkoti Ashutosh A Jordan Rainer R Luxenhofer Robert R
Macromolecular bioscience 20160112 3
The design of drug delivery systems capable of efficiently delivering poorly soluble drugs to target sites still remains a major challenge. Such materials require several different functionalities; typically, these materials should be biodegradable and nontoxic, nonimmunogenic, responsive to their environment, and soluble in aqueous solution while retaining the ability to solubilize hydrophobic drugs. Here, a polypeptide-polymer hybrid of elastin-like polypeptides (ELPs) and poly(2-oxazoline)s ( ...[more]