Ontology highlight
ABSTRACT:
SUBMITTER: Jang H
PROVIDER: S-EPMC5320989 | biostudies-literature | 2017 Feb
REPOSITORIES: biostudies-literature
Jang Heeun H Levy Sagi S Flavell Steven W SW Mende Fanny F Latham Richard R Zimmer Manuel M Bargmann Cornelia I CI
Proceedings of the National Academy of Sciences of the United States of America 20170131 7
A hub-and-spoke circuit of neurons connected by gap junctions controls aggregation behavior and related behavioral responses to oxygen, pheromones, and food in <i>Caenorhabditis elegans</i> The molecular composition of the gap junctions connecting RMG hub neurons with sensory spoke neurons is unknown. We show here that the innexin gene <i>unc-9</i> is required in RMG hub neurons to drive aggregation and related behaviors, indicating that UNC-9-containing gap junctions mediate RMG signaling. To d ...[more]