Ontology highlight
ABSTRACT:
SUBMITTER: Cao MD
PROVIDER: S-EPMC5321748 | biostudies-literature | 2017 Feb
REPOSITORIES: biostudies-literature
Cao Minh Duc MD Nguyen Son Hoang SH Ganesamoorthy Devika D Elliott Alysha G AG Cooper Matthew A MA Coin Lachlan J M LJ
Nature communications 20170220
Third generation sequencing technologies provide the opportunity to improve genome assemblies by generating long reads spanning most repeat sequences. However, current analysis methods require substantial amounts of sequence data and computational resources to overcome the high error rates. Furthermore, they can only perform analysis after sequencing has completed, resulting in either over-sequencing, or in a low quality assembly due to under-sequencing. Here we present npScarf, which can scaffo ...[more]