Rtfc (4931414P19Rik) Regulates in vitro Thyroid Differentiation and in vivo Thyroid Function.
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ABSTRACT:
SUBMITTER: Yu Y
PROVIDER: S-EPMC5322522 | biostudies-literature | 2017 Feb
REPOSITORIES: biostudies-literature
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Rtfc (4931414P19Rik) Regulates in vitro Thyroid Differentiation and in vivo Thyroid Function.
Yu Yang Y Liu Chang C Zhang Junxia J Zhang Mimi M Wen Wei W Ruan Xianhui X Li Dapeng D Zhang Shuang S Gao Ming M Chen Lingyi L
Scientific reports 20170223
Thyroid is a one of the most important endocrine organs. Understanding the molecular mechanism underlying thyroid development and function, as well as thyroid diseases, is beneficial for the clinical treatment of thyroid diseases and tumors. Through genetic linkage analysis and exome sequencing, we previously identified an uncharacterized gene C14orf93 (RTFC, mouse homolog: 4931414P19Rik) as a novel susceptibility gene for familial non-medullary thyroid carcinoma, and demonstrated its function i ...[more]
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