Ontology highlight
ABSTRACT:
SUBMITTER: Oikkonen L
PROVIDER: S-EPMC5322827 | biostudies-literature | 2017 Jan
REPOSITORIES: biostudies-literature
Oikkonen Laura L Lise Stefano S
Wellcome open research 20170117
Identifying variants from RNA-seq (transcriptome sequencing) data is a cost-effective and versatile alternative to whole-genome sequencing. However, current variant callers do not generally behave well with RNA-seq data due to reads encompassing intronic regions. We have developed a software programme called Opossum to address this problem. Opossum pre-processes RNA-seq reads prior to variant calling, and although it has been designed to work specifically with Platypus, it can be used equally we ...[more]