HPV16 E6 seropositivity among cancer-free men with oral, anal or genital HPV16 infection.
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ABSTRACT:
SUBMITTER: Beachler DC
PROVIDER: S-EPMC5322843 | biostudies-literature | 2016 Dec
REPOSITORIES: biostudies-literature
Publications
HPV16 E6 seropositivity among cancer-free men with oral, anal or genital HPV16 infection.
Beachler Daniel C DC Waterboer Tim T Pierce Campbell Christine M ChM Ingles Donna J DJ Kuhs Krystle A Lang KA Nyitray Alan G AG Hildesheim Allan A Pawlita Michael M Kreimer Aimée R AR Giuliano Anna R AR
Papillomavirus research (Amsterdam, Netherlands) 20160728
Antibodies against the Human papillomavirus 16 (HPV16) E6 oncoprotein appear years prior to clinical diagnosis of anal and oropharyngeal cancer, but whether they develop around the time of HPV infection is unclear. Serum samples from 173 cancer-free men from the Human Papillomavirus Infection in Men (HIM) Study were tested for HPV antibodies and DNA. HPV16 E6 seropositivity was low among men with oral HPV16-infection (1/28; 3.6%, 95%CI=0.0%-18.4%), anal HPV16-infection (1/61; 1.6%, 95%CI=0.0%-8. ...[more]
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