Ontology highlight
ABSTRACT:
SUBMITTER: Wang L
PROVIDER: S-EPMC5323202 | biostudies-literature | 2016 Oct
REPOSITORIES: biostudies-literature
Wang Liang L Li Gang G Liu Nan N Wang Zhen Z Xu Xiaoshan X Qi Jing J Ren Dongni D Zhang Pengxing P Zhang Yongsheng Y Tu Yanyang Y
Oncotarget 20161001 40
Gliomas make up about 80% of all malignant brain tumors, and cause serious public health problem. Genetic factors and environmental factors jointly caused the development of gliomas, and understanding of the genetic basis is a key component of preventive oncology. However, most genetic factors underlying carcinogenesis of gliomas remain largely unclear. In current study, we systematically evaluated whether genetic variants of SOX9 gene, a transcription factor that plays a central role in the dev ...[more]