Ontology highlight
ABSTRACT:
SUBMITTER: Lu J
PROVIDER: S-EPMC5323214 | biostudies-literature | 2016 Oct
REPOSITORIES: biostudies-literature
Lu Jiafei J Yin Yongmei Y Du Mulong M Ma Gaoxiang G Ge Yuqiu Y Zhang Qiang Q Chu Haiyan H Tong Na N Wang Meilin M Qiu Jinrong J Zhang Zhengdong Z
Oncotarget 20161001 40
Human 8-oxoguanine DNA glycosylase (hOGG1) is known to play an important role in the prevention of carcinogenesis, including gastric cancer (GC). We performed a case-control study to investigate whether single nucleotide polymorphisms (SNPs) of hOGG1 are associated with GC risk in a Chinese population. Two potential functional tagSNPs (rs159153 and rs1052133) and a previously reported risk SNP (rs125701) were genotyped in 1,275 GC patients and 1,436 controls. We found that SNP rs125701 G > A was ...[more]