A reliable and flexible gene manipulation strategy in posthatch zebra finch brain.
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ABSTRACT:
SUBMITTER: Ahmadiantehrani S
PROVIDER: S-EPMC5324116 | biostudies-literature | 2017 Feb
REPOSITORIES: biostudies-literature
Publications
A reliable and flexible gene manipulation strategy in posthatch zebra finch brain.
Ahmadiantehrani Somayeh S London Sarah E SE
Scientific reports 20170224
Songbird models meaningfully contribute to many fields including learned vocal communication, the neurobiology of social interactions, brain development, and ecology. The value of investigating gene-brain-behavior relationships in songbirds is therefore high. Viral infections typically used in other lab animals to deliver gene editing constructs have been less effective in songbirds, likely due to immune system properties. We therefore leveraged the in vivo electroporation strategy used in utero ...[more]
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