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The F-ATPase operon promoter of Streptococcus mutans is transcriptionally regulated in response to external pH.


ABSTRACT: Streptococcus mutans F-ATPase, the major component of the acid-adaptive response of the organism, is transcriptionally upregulated at low pH. Fusions of the F-ATPase promoter to chloramphenicol acetyltransferase indicated that pH-dependent expression is still observed with a short promoter that contains a domain conserved between streptococcal ATPase operons.

SUBMITTER: Kuhnert WL 

PROVIDER: S-EPMC532412 | biostudies-literature | 2004 Dec

REPOSITORIES: biostudies-literature

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The F-ATPase operon promoter of Streptococcus mutans is transcriptionally regulated in response to external pH.

Kuhnert Wendi L WL   Zheng Guolu G   Faustoferri Roberta C RC   Quivey Robert G RG  

Journal of bacteriology 20041201 24


Streptococcus mutans F-ATPase, the major component of the acid-adaptive response of the organism, is transcriptionally upregulated at low pH. Fusions of the F-ATPase promoter to chloramphenicol acetyltransferase indicated that pH-dependent expression is still observed with a short promoter that contains a domain conserved between streptococcal ATPase operons. ...[more]

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