Continuous measurement of aortic dimensions in Turner syndrome: a cardiovascular magnetic resonance study.

ABSTRACT:

Background

Severity of thoracic aortic disease in Turner syndrome (TS) patients is currently described through measures of aorta size and geometry at discrete locations. The objective of this study is to develop an improved measurement tool that quantifies changes in size and geometry over time, continuously along the length of the thoracic aorta.

Methods

Cardiovascular magnetic resonance (CMR) scans for 15 TS patients [41 ± 9 years (mean age ± standard deviation (SD))] were acquired over a 10-year period and compared with ten healthy gender and age-matched controls. Three-dimensional aortic geometries were reconstructed, smoothed and clipped, which was followed by identification of centerlines and planes normal to the centerlines. Geometric variables, including maximum diam

SUBMITTER: Subramaniam DR 

PROVIDER: S-EPMC5324249 | biostudies-literature | 2017 Feb

REPOSITORIES: biostudies-literature