Landscape of RNAs in human lumbar disc degeneration.
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ABSTRACT:
SUBMITTER: Lan PH
PROVIDER: S-EPMC5325354 | biostudies-literature | 2016 Sep
REPOSITORIES: biostudies-literature
Publications
Landscape of RNAs in human lumbar disc degeneration.
Lan Ping-Heng PH Liu Zhi-Heng ZH Pei Yan-Jun YJ Wu Zhi-Gang ZG Yu Yang Y Yang Yong-Feng YF Liu Xu X Che Lu L Ma Chi-Jiao CJ Xie Yan-Ke YK Hu Qing-Jie QJ Wan Zhong-Yuan ZY Wang Hai-Qiang HQ
Oncotarget 20160901 39
Accumulating evidence indicates noncoding RNAs (ncRNAs) fine-tune gene expression with mysterious machinery. We conducted a combination of mRNA, miRNA, circRNA, LncRNA microarray analyses on 10 adults' lumbar discs. Moreover, we performed additional global exploration on RNA interacting machinery in terms of in silico computational pipeline. Here we show the landscape of RNAs in human lumbar discs. In general, the RNA-abundant landscape comprises 14,635 mRNAs (37.93%), 2,059 miRNAs (5.34%), 18,9 ...[more]
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