Ontology highlight
ABSTRACT:
SUBMITTER: Ying Q
PROVIDER: S-EPMC5325379 | biostudies-literature | 2016 Sep
REPOSITORIES: biostudies-literature
Ying Qikang Q Ma Tiejun T Cheng Linfeng L Zhang Xiaoxiao X Truax Agnieszka D AD Ma Ruixue R Liu Ziyu Z Lei Yingfeng Y Zhang Liang L Ye Wei W Zhang Fanglin F Xu Zhikai Z Shang Lei L Liu Rongrong R Wang Fang F Wu Xingan X
Oncotarget 20160901 39
Infection of Hantaan virus (HTNV) usually causes hemorrhagic fever with renal syndrome (HFRS). China has the worst epidemic incidence of HFRS as well as high fatality. Inactivated whole virus has been used for HFRS vaccination, however there are still problems such as safety concerns. CD40 ligand (CD40L) and granulocyte macrophage colony-stimulating factor (GM-CSF) are well-known immune stimulating molecules that can enhance antigen presenting, lymphocytes activation and maturation, incorporatio ...[more]