Various Sequence Types of Escherichia coli Isolates Coharboring blaNDM-5 and mcr-1 Genes from a Commercial Swine Farm in China.
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ABSTRACT:
SUBMITTER: Kong LH
PROVIDER: S-EPMC5328568 | biostudies-literature | 2017 Mar
REPOSITORIES: biostudies-literature
Publications
Various Sequence Types of Escherichia coli Isolates Coharboring <i>bla</i><sub>NDM-5</sub> and <i>mcr-1</i> Genes from a Commercial Swine Farm in China.
Kong Ling-Han LH Lei Chang-Wei CW Ma Su-Zhen SZ Jiang Wei W Liu Bi-Hui BH Wang Yong-Xiang YX Guan Ru R Men Shuai S Yuan Qi-Wu QW Cheng Guang-Yang GY Zhou Wen-Cheng WC Wang Hong-Ning HN
Antimicrobial agents and chemotherapy 20170223 3
Sixteen different sequence types (STs) of <i>Escherichia coli</i> isolates from a commercial swine farm in China were confirmed to coharbor the carbapenem resistance gene <i>bla</i><sub>NDM-5</sub> and the colistin resistance gene <i>mcr-1</i> Whole-genome sequencing revealed that <i>bla</i><sub>NDM-5</sub> and <i>mcr-1</i> were located on a 46-kb IncX3 plasmid and a 32-kb IncX4 plasmid, respectively. The two plasmids can transfer together with a low fitness cost, which might explain the presenc ...[more]
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