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Simulating and optimizing compound refractive lens-based X-ray microscopes.

ABSTRACT: A comprehensive optical description of compound refractive lenses (CRLs) in condensing and full-field X-ray microscopy applications is presented. The formalism extends ray-transfer matrix analysis by accounting for X-ray attenuation by the lens material. Closed analytical expressions for critical imaging parameters such as numerical aperture, spatial acceptance (vignetting), chromatic aberration and focal length are provided for both thin- and thick-lens imaging geometries. These expressions show that the numerical aperture will be maximized and chromatic aberration will be minimized at the thick-lens limit. This limit may be satisfied by a range of CRL geometries, suggesting alternative approaches to improving the resolution and efficiency of CRLs and X-ray microscopes.

SUBMITTER: Simons H

PROVIDER: S-EPMC5330290 | biostudies-literature | 2017 Mar

REPOSITORIES: biostudies-literature

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Simulating and optimizing compound refractive lens-based X-ray microscopes.

Simons Hugh H Ahl Sonja Rosenlund SR Poulsen Henning Friis HF Detlefs Carsten C

Journal of synchrotron radiation 20170220 Pt 2

A comprehensive optical description of compound refractive lenses (CRLs) in condensing and full-field X-ray microscopy applications is presented. The formalism extends ray-transfer matrix analysis by accounting for X-ray attenuation by the lens material. Closed analytical expressions for critical imaging parameters such as numerical aperture, spatial acceptance (vignetting), chromatic aberration and focal length are provided for both thin- and thick-lens imaging geometries. These expressions sho ...[more]

PMID: 28244432

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