Dataset Information

Resection and reconstruction following recurrent malignant phyllodes-Case report and review of literature.

ABSTRACT:

Introduction

Phyllodes tumors are uncommon biphasic fibroepithelial neoplasms of the breast of varying malignant potential occurring in middle aged women. They exhibit diverse biological behavior. Margin free excision is the mainstay of treatment.

Case presentation

A 27 year-old lady was referred with a painless ulceroproliferative right breast lesion which had rapidly progressed over six months. Three years back, she had been diagnosed with a borderline phyllodes tumor and underwent a wide local excision followed by a right mastectomy for recurrence. The resection margins were positive hence she underwent postoperative radiation. We performed a radical resection of the chest wall and reconstruction using a composite mesh (inner PTFE and outer vypro), pedicled latissimus dorsi flap and a split skin graft for the recurrent malignant tumor. She recovered uneventfully thereafter.

Discussion

Malignant phyllodes tumor is uncommon and treatment principles are from case reports and retrospective studies. Aggressive resection of the lesion and reconstruction of the chest wall with bone cement and two meshes-a composite mesh (inner layer -polytetrafluroethylene and outer layer of polypropylene) and a Vypro mesh is a possibility. This case highlights the challenges encountered in managing these patients and presents a radical solution.

Conclusion

Treatment of phyllodes tumor necessitates adequate excision of the tumor and adjacent tissues to ensure tumor free margins. Pathological evolution from intermediate to malignant histology may be exhibited. A full-thickness chest wall resection and reconstruction although radical is a feasible option as these tumors rarely respond to other modalities of cancer management.

SUBMITTER: Rajesh A

PROVIDER: S-EPMC5331157 | biostudies-literature | 2017 Apr

REPOSITORIES: biostudies-literature

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Publications

Resection and reconstruction following recurrent malignant phyllodes-Case report and review of literature.

Rajesh Aashish A Farooq Mohammed M

Annals of medicine and surgery (2012) 20170221

<h4>Introduction</h4>Phyllodes tumors are uncommon biphasic fibroepithelial neoplasms of the breast of varying malignant potential occurring in middle aged women. They exhibit diverse biological behavior. Margin free excision is the mainstay of treatment.<h4>Case presentation</h4>A 27 year-old lady was referred with a painless ulceroproliferative right breast lesion which had rapidly progressed over six months. Three years back, she had been diagnosed with a borderline phyllodes tumor and underw ...[more]

PMID: 28275427

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Dataset Information

Resection and reconstruction following recurrent malignant phyllodes-Case report and review of literature.

Introduction

Case presentation

Discussion

Conclusion

Publications

Resection and reconstruction following recurrent malignant phyllodes-Case report and review of literature.

Similar Datasets

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