Ontology highlight
ABSTRACT:
SUBMITTER: Schaefer EJ
PROVIDER: S-EPMC5331615 | biostudies-literature | 2016 Sep - Oct
REPOSITORIES: biostudies-literature
Schaefer Ernst J EJ Anthanont Pimjai P Diffenderfer Margaret R MR Polisecki Eliana E Asztalos Bela F BF
Progress in cardiovascular diseases 20160824 2
Low serum high density lipoprotein cholesterol level (HDL-C) <40 mg/dL in men and <50 mg/dL in women is a significant independent risk factor for cardiovascular disease (CVD), and is often observed in patients with hypertriglyceridemia, obesity, insulin resistance, and diabetes. Patients with marked deficiency of HDL-C (<20 mg/dL) in the absence of secondary causes are much less common (<1% of the population). These patients may have homozygous, compound heterozygous, or heterozygous defects inv ...[more]