Dataset Information

Association of Ambient Air Pollution with Depressive and Anxiety Symptoms in Older Adults: Results from the NSHAP Study.

ABSTRACT:

Background

Ambient fine particulate matter (PM_2.5) is among the most prevalent sources of environmentally induced inflammation and oxidative stress, both of which are implicated in the pathogenesis of most mental disorders. Evidence, however, concerning the impact of PM_2.5 on mental health is just emerging.

Objective

We examined the association between PM_2.5 and current level of depressive and anxiety symptoms using a nationally representative probability sample (n = 4,008) of older, community-dwelling individuals living across the United States (the National Social Life, Health and Aging project).

Methods

Mental health was evaluated using validated, standardized questionnaires and clinically relevant cases were identified using well-established cutoffs; daily PM_2.5 estimates were obtained using spatiotemporal models. We used generalized linear mixed models, adjusting for potential confounders, and explored effect modification.

Results

An increase in PM_2.5 was significantly associated with anxiety symptoms, with the largest increase for 180-days moving average (OR = 1.61; 95% CI: 1.35, 1.92) after adjusting for socioeconomic measures (SES); PM_2.5 was positively associated with depressive symptoms, and significantly for 30-day moving average (OR = 1.16; 95% CI: 1.05, 1.29) upon SES adjustment. The observed associations were enhanced among individuals who had low SES and history of comorbidity. When considering mental health as chronic conditions, PM_2.5 was significantly associated with incident depressive symptoms for all exposure windows examined, but with incident anxiety symptoms only for shorter exposure windows, which may be due to a drop in power resulting from the decreased between-subject variability in chronic PM_2.5 exposure.

Conclusion

PM_2.5 was associated with depressive and anxiety symptoms, with associations the strongest among individuals with lower SES or among those with certain health-related characteristics. Citation: Pun VC, Manjourides J, Suh H. 2017. Association of ambient air pollution with depressive and anxiety symptoms in older adults: results from the NSHAP study. Environ Health Perspect 125:342-348;?http://dx.doi.org/10.1289/EHP494.

SUBMITTER: Pun VC

PROVIDER: S-EPMC5332196 | biostudies-literature | 2017 Mar

REPOSITORIES: biostudies-literature

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Publications

Association of Ambient Air Pollution with Depressive and Anxiety Symptoms in Older Adults: Results from the NSHAP Study.

Pun Vivian C VC Manjourides Justin J Suh Helen H

Environmental health perspectives 20160812 3

<h4>Background</h4>Ambient fine particulate matter (PM<sub>2.5</sub>) is among the most prevalent sources of environmentally induced inflammation and oxidative stress, both of which are implicated in the pathogenesis of most mental disorders. Evidence, however, concerning the impact of PM<sub>2.5</sub> on mental health is just emerging.<h4>Objective</h4>We examined the association between PM<sub>2.5</sub> and current level of depressive and anxiety symptoms using a nationally representative prob ...[more]

PMID: 27517877

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Dataset Information

Association of Ambient Air Pollution with Depressive and Anxiety Symptoms in Older Adults: Results from the NSHAP Study.

Background

Objective

Methods

Results

Conclusion

Publications

Association of Ambient Air Pollution with Depressive and Anxiety Symptoms in Older Adults: Results from the NSHAP Study.

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